Increasing demand for therapeutic drugs including pharmaceuticals, biopharmaceuticals, and biologics is the major factor to grow pyrogen testing market

The global pyrogen testing market is expected to reach a value of USD 1.9 billion by 2025, according to a new report by Grand View Research, Inc. Increasing demand for therapeutic drugs including pharmaceuticals, biopharmaceuticals, and biologics is the major factor that propels growth of the market during forecast period. Pyrogen is a toxic molecular substance that causes fever if induced in animal or human body. Pyrogen testing is used by pharmaceutical, biopharmaceuticals, biotechnology, and medical devices companies to confirm the absence of pyrogen. Thus, the companies use various methods such as LAL, in vitro pyrogen, and rabbit test to ensure the quality of products.

Increasing prevalence of chronic diseases, is another foremost factor supporting the growth of the pyrogen testing market. The prevalence of chronic diseases is very high in developed countries and is growing at high pace in developing countries including China and India. Different factors such as unhealthy diet, smoking, alcohol consumption, and lack of exercise leads to occurrence of chronic diseases such as cancer, cardiovascular diseases, diabetes, and chronic respiratory diseases.  Hence, there is a growing demand for therapeutic drugs and medical devices for the treatment of such diseases, which in turn is projected to fuel the demand for pyrogen testing to ensure the quality of products including drugs and devices.

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Further key findings from the study suggest:

• Consumables was the largest revenue grossing segment of the pyrogen testing market in 2016, owing to the large application of pyrogen testing kits and reagents along with its repetitive purchase
• Instruments segment accounted for the remarkable share in the market in 2016 and is also expected to showcase significant growth during forecast period, owing to rising demand for pharmaceutical, biologics, and medical devices for treatment and diagnosis
• The pharmaceutical and biotechnology companies segment dominated the pyrogen testing market in terms of revenue in 2016, due to the large production of therapeutic drugs and growing investment in R&D by companies for drug development
• North America is the leading regional market and accounted for the largest revenue share in 2016 primarily due to the existence of large number of healthcare companies including pharmaceuticals and medical devices in this region
• The Asia Pacific region is anticipated to be the fastest growing market during the study period. The growing prevalence rate of chronic diseases in the Asian countries including India and China, is a major factor contributing to the expansion of market in this region.
• Some major players serving this vertical include Charles River Laboratories, Inc.; Ellab A/S; Merck KGaA; GenScript; Hyglos GmbH; Lonza; Thermo Fisher Scientific, Inc.; Associates of Cape Cod, Inc.; and Pyrostar

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Surging demand for anti-wrinkle creams, anti-aging solutions, and expanding cosmetic industry contribute to the growth hyaluronic acid row material market

The global hyaluronic acid raw material market is expected to reach a value of USD 7.25 billion by 2024, according to a new report by Grand View Research, Inc. The increasing use of hyaluronic acid in various medical applications, such as osteoarthritis, wound healing, postoperative adhesion, tympanic membrane repair, tumor diagnosis, fracture healing, and soft tissue repair is expected to fuel the market growth over the forecast period.

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The orthopedics segment dominated the overall market in 2015 with the highest revenue generation. The increasing geriatric population base, rising incidence of osteoarthritis, and growing adoption of viscosupplements in the treatments contribute to the large market share of this segment. Furthermore, the drug delivery segment is projected to be the fastest growing over the forecast period with a significantly higher CAGR. The increasing R&D activities focusing on targeted drug delivery systems and growing usage of hyaluronic acid in anti-cancer drug delivery is expected to contribute to the market growth.

The increasing women population of age 35 to 65 years across the globe engenders a greater demand for anti-aging cosmetic and aesthetic treatments. Owing to the distinctive viscoelastic and moisturizing properties coupled with lower toxicity levels offered by hyaluronic acid-based products, the demand for this polymer in dermal fillers as well as in the treatment of vesicoureteral reflux is expected to experience growth. Thus, it is anticipated that the need for such products will serve as a high impact driver for the hyaluronic acid products over the forecast period. Based on the statistics of the International Society of Aesthetic Plastic Surgery in 2014, there were approximately 20 million cosmetic procedures performed globally, of which nearly 13.5% of the procedures were HA-based non-surgical procedures.

Some of the top countries recording a majority of the aesthetic treatments in 2014 were the U.S., Brazil, Japan, South Korea, Mexico, Germany, France, and Colombia. Medical tourism for cosmetic surgery in the U.S. plays a very important role in aiding the uptake of HA-based products and procedures, which is expected to drive the market in the coming few years.

Further Key Findings From the Study Suggest:

• In 2015, orthopedics was the largest application segment, owing to rising prevalence and incidence of osteoarthritis
• The introduction of FDA-approved hyaluronic acid-based viscosupplements such as ORTHOVISC and MONOVISC is expected to boost usage over the next 8 years
• Some of the key market players are Salix Pharmaceuticals; ALLERGAN; Lifecore Biomedical, LLC; Shiseido Co., Ltd.; Anika Therapeutics, Inc.; Smith & Nephew; Maruha Nichiro Corporation; Ferring B.V.; SEIKAGAKU CORPORATION; Genzyme Corporation; F. Hoffmann-La Roche Ltd., Contipro a.s.; Zimmer Biomet; and others

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Technological advancement in molecular biology products, such as PCR and NGS is key factor contributing toward growth of molecular weight marker market

The global molecular weight marker market is expected to reach a value of USD 1.1 billion by 2025, according to a new report by Grand View Research, Inc. Increasing investment in R&D by companies including biotechnology and biologics is the major factor that drives the growth during the forecast period. These markers are used by researchers and companies for various applications such as polymerase chain reaction (PCR), northern blotting, southern blotting, and molecular cloning. Thus, the increasing application of these products in R&D is expected to boost growth.

Increasing focus on molecular biology research is another major factor supporting the growth of the molecular weight marker market. Molecular biology research is important to understand interactions between the different systems of a cell, including DNA, RNA, and protein biosynthesis & regulation. Thus, these research activities are very high in developed countries and are growing at a high pace in developing countries including China and India. Hence, there is a growing demand for molecular weight marker for research activities, which is expected to fuel the growth.

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Further key findings from the study suggest:

• DNA markers was the largest revenue-generating segment of the molecular weight marker market in 2016 and is also expected to showcase the fastest growth during forecast period
• In the application segment, nucleic acid accounted for the largest share in 2016, owing to the large application of DNA markers in PCR, sequencing, northern blotting, southern blotting, and molecular cloning
• The academic and research institutes dominated the molecular weight marker market in terms of revenue in 2016, due to the large focus on molecular biology and other related research activities
• The North America molecular weight market is the leading regional sector and accounted for the largest revenue share in 2016, mainly due to the existence of large number of research laboratories and biotechnology companies in this region
• The Asia Pacific market is projected to grow at a highest growth rate during the forecast period. The developing healthcare infrastructure and escalating interest on molecular research in the Asian countries such as India and China is a major factor contributing to the growth in this region
• Some of the major players include Thermo Fisher Scientific, Inc.; F Hoffmann-La Roche Ltd.; Merck KGaA; Agilent Technologies; QIAGEN; TAKARA BIO, INC.; Bio-Rad Laboratories, Inc.; Promega Corporation; and New England Biolabs

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Rising incidences of sports related injuries worldwide is anticipated to be high impact rendering driver for the lucrative growth of sports medicine market

The global sports medicine market is expected to reach USD 12.5 billion by 2025, according to a new report by Grand View Research, Inc. Rising incidences of sports related injuries worldwide is anticipated to be high impact rendering driver for the lucrative growth of sports medicine market.

As per data published by the U.S. Consumer Product Safety Commission’s National Electronic Injury Surveillance System (NEISS) in 2012, around 1.9 million people encountered such injuries. Additionally, with aid of fitness awareness initiatives from government and health organizations, people nowadays are more focused on physical exercise including gym, outdoor sports and others fitness activities. With this people are more prone to injuries, hence contributing to the remunerative growth of market.

Additionally, influx of technologically advanced products such as minimally invasive surgical products is anticipated to increase the demand for these devices over the forecast period. For instance, in March 2015, Smith & Nephew launched Q-FIX implant which assists surgeon’s flexibility for all sutures anchors along with fixation and pull-out strength equivalent to large sized anchors.

Similarly, in May 2014 Smith & Nephew acquired ArthroCare, a medical device company based in the U.S. specialized in tissue repair devices. This acquisition helped the company to enrich its sports medicine product portfolio.

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Further key findings from the study suggest:

• Body reconstruction and repair devices consisting of surgical equipment, soft tissue repair, and bone reconstruction devices held significant share in 2016 and also this segment is anticipated to exhibit lucrative growth rate over the forecast period.
• Knee-related applications held largest market share in 2016.The knee injuries are the most frequent in most of the games such as soccer, basketball, bicycle, and running which supported the dominion in application segment.
• In the therapeutic segment, cardiology, IVD, and drug delivery are the top performing segments. Rising incidences of cardiac failures, infectious diseases and high research activity in the field of drug delivery are certain vital impact rendering factors.
• North America, held commanding shares in global sports medicine market. Improved healthcare infrastructure and high healthcare expenditure are key factors responsible for growth. In addition, presence of organizations which are dedicated in field of sports medicine such as the American College of Sports Medicine (ACSM) facilitated availability of adequate and qualified staff.
• The key players of the industry include Stryker Corporation, Arthrex, ArthroCare, Tornier N.V., Wright Medical Technology, DJO Global, Otto Bock Healthcare, Ossur HF, Zimmer Holdings Inc., and Smith & Nephew Plc.

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Rat model market is predicted to witness higher revenue contribution by breeding process

The global rat model market is expected to reach USD 845.0 million by 2025, according to a new report by Grand View Research, Inc. As of 2016, outbred type of rat model is commonly utilized for research and educational activities within the healthcare domain. However, advancement in production technologies is expected to boost growth of knockout and conditioned rats.

The production technologies for aforementioned type of model are recent in nature and can be traced back to 2008, post the development of mobile DNA technology. The first knockout model was introduced in 2009 using Zinc Finger Nuclease (ZFN) method, which led to an advancement in the field of rat models. Other tools for genetic editing are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), homologous recombination, and N-ethyl-N-nitrosourea (ENU) mutagenesis.

Furthermore, supportive infrastructure and technology coupled with growing incidence of chronic conditions & genetic mutation amongst human species are expected to extend higher applicability for research purposes, thereby boosting growth.

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Further key findings from the study suggest:

• Outbred is expected to dominate the type segment for rat model market. Presence of numerous outbred type and higher applicability of these to mimic human diseases is anticipated to support growth over the forecast period.
• Microinjection is anticipated to witness the fastest growth over the forecast period owing to faster development of the models and reduction in breeding time. Similarly, development of newer technology within the other segment is expected to propel growth.
• Based on services, the rat model market is predicted to witness higher revenue contribution by breeding process. Cryopreservation is anticipated to witness fastest growth over the forecast period.
• Rising production of conditioned rats for behavioral studies and growing R&D within neurological application is expected to support lucrative growth of rat model. Other application expected to support growth include cardiovascular disorders, diabetes, obesity, and renal disorders.
• The key market players of the industry include Covance Inc.; Envigo; Charles River Laboratories International, Inc.; Horizon Discovery Group plc.; TransViragen, Inc.; Javier Labs; and others. Mergers & acquisitions are expected to strengthen company capabilities. For instance, Horizon Discovery Group plc. accomplished the aforementioned goal by acquiring SAGE Labs, Inc. in 2014.

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Rising number of diabetic population and awareness level regarding the usage of insulin pens are key factors to growth pen needle market

The global pen needles market is expected to reach a value of USD 4.8 billion by 2025, according to a new report by Grand View Research, Inc. Rising prevalence of diabetes is the primary reason for the significant growth of pen needles market. According to the International Diabetes Federation (IDF), nearly 415 million people were suffering from diabetes in 2015. Such a high prevalence of diabetes across the globe has led to rising demand for pen needles. Patients suffering from diabetes commonly use injectable pen devices, which helps in easy drug delivery.

In addition, obesity is a significant cause of diabetes. Obese people often suffer from type 2 diabetes, which makes them one of the highest revenue contributors of the target market. Thus, people with type 2 diabetes are the common target population for companies manufacturing pen needles.

Rising technological advancements is also expected to drive the market growth. Pen needles allow comfort and easy mode of insulin delivery. These devices are technologically advanced and provide a superior alternative drug delivery method in comparison to syringes and vials. For instance, in 2013, Becton, Dickinson and Company launched BD Ultra-Fine Nano 4mm Pen Needles with EasyFlow Technology, which will enable diabetic patients with easy adherence of insulin therapy regimens.

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Further Key Findings from the Study Suggest:

• Standard needles dominated the market in 2015 due to the availability of cost-effective needles as compared to safety needles
• Safety pen needles are anticipated to showcase lucrative growth over the forecast period due to the continuous technological advancements
• Amongst the needle lengths, 8mm held the largest share in 2015. This is due to the convenience offered by this needle type on diabetic patients
• Needle length of 4mm are expected to witness attractive CAGR over the forecast period owing to its short length
• Insulin therapy accounted for the largest market share in 2015 due to rising awareness regarding self-administration of insulin amongst the diabetic patients
• Europe dominated the market in 2015 followed by North America owing to high prevalence of diabetes in the European region
• Asia Pacific region is anticipated to exhibit the highest growth rate over the forecast period owing to the rising awareness levels amongst the diabetic population regarding easy drug delivery
• Some of the key players include Becton, Dickinson and Company, B. Braun Melsungen AG, Novo Nordisk A/S, Owen Mumford, Ltd., Ypsomed, HTL-STREFA, and TERUMO CORPORATION.

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Demand of cell culture protein surface coating is growing at a high rate, which is estimated to drive the growth of cell culture protein surface coating market

The global cell culture protein surface coating market is expected to reach a value of USD 1.3 billion by 2025, according to a new report by Grand View Research, Inc. Increasing focus on stem cell research and development is the most substantial factor that drives the market growth during the forecast period. Stem cell therapy is the most promising method to treat severe medical conditions such as cardiovascular disease, brain disease, cell deficiency therapy, and blood disease. Thus, the biotechnology companies and research laboratories are adopting innovative protein surface coating products for the development of stem cells.

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Rising demand for biopharmaceutical products including antibodies, vaccines, proteins, and drugs is another major factor driving the growth of the cell culture protein surface coating market. The production of biopharmaceutical products such as monoclonal antibodies and recombinant proteins is carried out by using cell culture technique. The protein surface coating provides improved adhesion and proliferation of cells in vitro. Thus, the demand of cell culture protein surface coating is growing at a high rate, which is estimated to drive the growth of this sector.

Further key findings from the study suggest:

• Self-coating was the largest revenue grossing segment of the cell culture protein surface coatingmarket in 2015. It is expected to uphold its dominance during the forecast period owing to its large application in 2D and 3D cell cultures
• The precoated product segment is the fastest growing segment due to growing popularity of multiwell/microwell plates for in vitro applications
• The synthetic protein segment is anticipated to grow at the fastest rate during forecast period, due to its advantages over other protein types such as reduced risk of contamination and simplified composition
• North America was the largest revenue-generating region of the market in the year 2015. This region is expected to maintain its position during the forecast period
• Existence of big biopharmaceutical companies and highly developed healthcare infrastructure is projected to drive the demand for products of the target market in the region during forecast period
• Asia Pacific region is anticipated to be the fastest growing segment over the forecast period
• Rapidly booming biotechnology industry and comparatively less stringent regulations for biologics development in APAC region is primarily driving the growth of this sector
• Some of the key players include Corning Inc.; Merck KGaA; Thermo Fisher Scientific, Inc.; Greiner Bio One International GmbH; PerkinElmer, Inc.; BioVision, Inc.; and Trevigen Inc.